My experience in Italy was nothing short of magical, and I want everyone to feel the same awe and wonder I did as I explored the ancient ruins of Rome, wandered the Renaissance streets of Florence, and sailed through the enchanting canals of Venice. From savoring authentic Italian cuisine to discovering hidden gems, this journey is one I hope to inspire in every traveler ready to fall in love with Italy’s charm, history, and beauty.

12-Day Self-Guided Italy Itinerary: Rome, Florence, and Venice

If you're dreaming of an immersive Italian experience that combines culture, food, and stunning landscapes, this 12-day self-guided itinerary is perfect for you. Having explored these places myself, I can tell you this journey is an unforgettable one, from the historic wonders of Rome to the Renaissance magic of Florence and the romantic canals of Venice. Let’s dive in day by day, with details on how to get around, where to stay, and the best places to eat, as well as links to tours and restaurants you can book.

Day 1-4: Rome – The Eternal City

Day 1: Arrival in Rome

After landing in Rome Fiumicino Airport, take a direct train (Leonardo Express) to Roma Termini (about 30 minutes). From here, a quick taxi ride or walk will bring you to your hotel. I stayed at Hotel Artemide, an elegant spot with modern comforts and a central location, perfect for exploring the city on foot.

Day 2: The Heart of Rome

Start your Roman adventure with a visit to the Colosseum and Roman Forum. I recommend pre-booking a skip-the-line tour with GetYourGuide, which made it incredibly easy to breeze through the lines. Spend the afternoon wandering around the Pantheon and Piazza Navona before treating yourself to the best gelato at Giolitti.

For dinner, book a table at Armando al Pantheon, a cozy, family-run trattoria serving traditional Roman dishes like Cacio e Pepe.

Day 3: Vatican and Trastevere

Head to the Vatican Museums and St. Peter's Basilica (another one to book in advance through Vatican Tours for skip-the-line access). You could spend hours here, but try to make time for a stroll along Via Giulia before crossing the river into Trastevere. This bohemian neighborhood is packed with vibrant nightlife and some of the best eateries. Dinner at Osteria Da Enzo al 29 is a must – their carbonara is mouthwatering!

Day 4: Rome to Florence

After breakfast, catch a high-speed train (Frecciarossa) from Roma Termini to Firenze Santa Maria Novella. The ride takes about 1.5 hours, and it's a comfortable way to travel through Italy's countryside.

Day 5-8: Florence – Renaissance Magic

Day 5: Arrival in Florence

Florence is walkable, and staying central is key. I recommend Hotel Brunelleschi, a charming hotel just steps away from the Duomo. Once you’ve settled in, explore Piazza della Signoria and marvel at Palazzo Vecchio.

For a first-night treat, dine at Il Santo Bevitore, a fantastic restaurant offering modern takes on Tuscan classics.

Day 6: Art & Culture

Start with a visit to Galleria dell'Accademia to see Michelangelo’s David, then head over to Uffizi Gallery for a deep dive into Renaissance art. Both museums are best experienced with a guided tour to avoid long lines – I used Florence Tours for an excellent experience.

For lunch, grab a bite at Mercato Centrale where you can enjoy fresh pasta, meats, and cheeses. Don’t miss the panoramic views from Piazzale Michelangelo at sunset – it's truly breathtaking!

Day 7: Tuscany Day Trip

Rent a car or book a wine-tasting tour to Chianti (I booked mine through GetYourGuide, and the vineyards were stunning). Driving through the Tuscan countryside feels like stepping into a painting. You’ll visit charming towns like Greve and Panzano, enjoying local wine and food along the way.

Dinner back in Florence at Trattoria Mario for a no-fuss meal with a Florentine steak that will blow your mind.

Day 8: Florence to Venice

After breakfast, board another high-speed train (Frecciarossa) from Firenze Santa Maria Novella to Venezia Santa Lucia. The journey takes about 2 hours. Once you arrive, it's a short vaporetto ride to your hotel.

Day 9-12: Venice – The Floating City

Day 9: Arrival in Venice

I stayed at Ca' Sagredo Hotel, a stunning palazzo overlooking the Grand Canal. Spend the afternoon wandering the narrow streets, visit Rialto Bridge, and sip a coffee in Piazza San Marco.

For dinner, try Osteria alle Testiere, a small seafood restaurant known for its fresh Venetian cuisine. Reservations are essential!

Day 10: Explore Venice

Book a private gondola ride for the full Venetian experience through Venice Tours. Afterward, visit St. Mark’s Basilica and Doge’s Palace. Both sites can be crowded, so I recommend booking skip-the-line tickets in advance.

Lunch at Trattoria alla Madonna, where you can sample Venice’s famous seafood risotto.

Day 11: Murano & Burano

Take a half-day boat tour to Murano (famous for glassmaking) and Burano (known for its brightly colored homes and lace). I loved the vibrant atmosphere of Burano and enjoyed a quiet lunch at Riva Rosa with stunning canal views.

Back in Venice, finish your last night with a romantic dinner at Ristorante Quadri, overlooking Piazza San Marco.

Day 12: Departure

Spend your last morning soaking up Venice’s unique charm. Stroll along the Grand Canal or visit a local bakery for one final Italian pastry before heading to Venice Marco Polo Airport for your flight home. You can book a private water taxi transfer directly to the airport through VeniceLink.

Getting Around

• Trains: Italy’s high-speed trains are comfortable and easy to use. Book tickets through Trenitalia or Italo.

• Vaporetto: In Venice, water buses (Vaporetto) are a great way to get around. Buy tickets from ACTV.

Around Italy In 12 Days